DNA Fragmentation Index (DFI) A Path To Parenthood
The DFI test stands for DNA Fragmentation Index test. This test checks the quality of DNA in the head of a sperm.
Sperm DNA is stored in the sperm’s head within long, thread-like structures called chromosomes. During sperm formation, the DNA strands combine to form chromosomes. However, if this process doesn’t happen correctly, it can cause breaks in the DNA strands. These breaks can affect the ability of the DNA to replicate during fertilization, which may lead to problems in forming healthy embryos.
The DFI test is important because it helps evaluate sperm DNA quality, which plays a key role in male fertility and successful pregnancies. If there are issues with DNA integrity, it might impact fertilization or embryo development. This test is often suggested for couples facing fertility challenges.
Sperm plays a key role in delivering male genetic material to the egg. The quality of this DNA is crucial for embryo development and pregnancy success.
A standard semen analysis checks sperm motility, concentration, and shape but does not assess the DNA quality. To evaluate sperm DNA integrity, specialists use the DNA Fragmentation Index (DFI) test. This test measures the amount of DNA damage (breaks) in sperm and provides a clearer picture of sperm quality.
Tthe DFI test is performed in a specialized andrology lab linked to IVF clinics. Our experts use the Sperm Chromatin Dispersion technique to identify sperm with high DNA fragmentation. This method ensures precise results and helps fertility specialists make better decisions for treatment.
If you’re facing fertility issues, the DFI test can give valuable insights into sperm health, guiding your journey toward successful conception.
Sperm quality depends on the level of damage to its DNA, known as DNA fragmentation. This damage is not related to the standard measures like count, motility, or shape in routine semen analysis.
However, high levels of DNA fragmentation strongly affect the sperm's ability to lead to a successful pregnancy, even with advanced techniques like IUI, IVF, or ICSI. Testing for sperm DNA fragmentation can uncover the reasons behind many cases of "unexplained" infertility.
With the help of this test, couples struggling with infertility can get better insights into their condition. This allows specialists to offer targeted solutions and improve the chances of success in treatments.
At our center, known for providing the Best infertility counselling & solution in Delhi, we aim to give couples accurate diagnoses and the most effective treatments for achieving their dream of parenthood. Consult us to explore the best options tailored to your needs.